Interleukin-12 (IL-12), produced by dendritic cells in response to activation, is central to pathogen eradication and tumor rejection.The trafficking pathways controlling spatial distribution and intracellular transport of IL-12 vesicles to the cell surface are still unknown.Here, we show that intracellular IL-12 localizes in late endocytic vesicle
Abstract During the winter months of 2020/2021 a wave of multisystem inflammatory syndrome in children (MIS-C) emerged in Poland.We present the results of Bumper (Pre-Runner Bar) a nationwide register aiming to capture and characterise MIS-C with a focus on severity determinants.The first MIS-C wave in Poland was notably high, hence our analysis in
A sequential multi-signature enabled multiple users to jointly sign a document in order.Xu,et al proposed a provably-secure certificateless sequential multi-signature scheme with constant signature length Dresser and pairing computations.However,it was shown that the scheme had a drawback in the verifying algorithm,and then it overcame the drawback
Manusia adalah makhluk Tuhan yang memiliki potensi istimewa dibandingkan dengan makhluk lain.Oleh karena itu, manusia Intimate Soap telah lama menjadi sebuah obyek kajian di kalangan psikolog dari berbagai aliran.Tiap aliran memandang manusia berdasarkan konsep dan metode yang diungkapkannya masing-masing.Hanya saja, aliran-aliran tersebut banyak y
Abstract Cervical Dystonia, also known as spasmodic torticollis, is a painful disorder in which the neck muscles spasm, causing the head to twist or swivel, pull in one direction, or shake (tremor).It may also result in a forward or backward head tilt.In certain instances, the hands may also shake or Dresser tremble.This project focuses on designin